Ethyl 4-[(E)-(2-hydroxybenzylidene)amino]piperidine-1-carboxylate
نویسندگان
چکیده
In the title compound, C(15)H(20)N(2)O(3), the piperidine ring adopts a chair conformation, although the amide N atom is almost planar (bond angle sum = 359.7°). The mol-ecule adopts an E conformation about the C=N bond, which allows for the formation of an intra-molecular O-H⋯N hydrogen bond. In the crystal, mol-ecules are linked by C-H⋯O inter-ations, resulting in C(6) chains propagating in [010].
منابع مشابه
tert-Butyl 4-(1-methyl-1H-pyrazol-5-yl)piperidine-1-carboxylate
The reaction of (E)-tert-butyl 4-[3-(dimethyl-amino)acrylo-yl]piperidine-1-carboxyl-ate with methyl-hydrazine leads to the formation of the title compound, C(14)H(23)N(3)O(2), with a 1-methyl-1H-pyrazol-5-yl substituent. The plane of the pyrazole ring forms a dihedral angle of 33.4 (1)° with the approximate mirror plane of the piperidine ring.
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The title compound, C18H20N2O3S, exists as the phenol-imine form in the crystal and there are bifurcated intra-molecular O-H⋯(N/O) hydrogen bonds present. The conformation about the C=N bond is anti (1E); the C=N imine bond length is 1.287 (4) Å and the C=N-C angle is 122.5 (3)°. In the tetrahydrothienopyridine moiety, the six-membered ring has a flattened-boat conformation. In the crystal, mol...
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In the title compound, C(27)H(32)N(2)O(4), the piperidine and tetra-hydro-pyridine rings adopt chair and half-chair conformations, respectively. The dihedral angle between the two phenyl rings is 32.9 (1)°. The mol-ecular structure is stabilized by a strong intra-molecular O-H⋯O hydrogen bond, generating an S(6) motif. In the crystal, inter-molecular C-H⋯O inter-actions form a ribbon-like struc...
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